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10 Most Addictive Drugs

The definition of a drug is ‘any chemical substance that affects the central nervous system.’ Determining the most addictive drugs has been a challenge for researchers and results have been debatable throughout the years. In addition of this, approving a proper definition for ‘addiction’ and criteria by which it can be measured is fairly difficult. Here is the list of most addictive drugs given below:

1. Buprenorphine

Its addiction rating is 1.64, it is used for the purpose of opioid replacement therapy, or to help ease the transition off of harder drugs like heroin. In addition to that it is being used by opioid addicts to help beat their addiction, it is also sometimes prescribed off label to treat depression.

2. Standard Amphetamines

Its addiction rating is 1.67, these are common stimulants of the central nervous system that can be used recreationally to achieve a buzz, but are medically used to treat ADHD and wakefulness disorders such as narcolepsy. Amphetamine was discovered in the late 1880s and exists in the form of multiple stereoisomers. When people stop using these drugs, most of them experience a significant crash, characterized by drowsiness, increased hunger, reduced levels of dopamine and low arousal.

3. Benzodiazepines

Its addiction rating is 1.83, Xanax or Valium, these are classified as benzodiazepines, or sedative hypnotic drugs. They decrease activity in the central nervous system by acting on the neurotransmitter GABA in the brain. When a person constantly uses these drugs, tolerance is quickly established. These are also some of the most difficult drugs to quit because the withdrawal process tends to result in even worse anxiety than a person experienced prior to taking the drug.

4. Alcohol

Its addiction rating is 1.93, When going to restaurants, most of the adults end up getting some sort of alcoholic beverage. Alcohol is a completely legal substance and due to its widespread use and legality, most people underestimate its addiction potential. As a result of being completely legal in the United States for individuals 21 years of age or older, over 17 million Americans are thought to have an alcohol-related disorder.

5. Barbiturates

Its addiction rating is 2.01, Barbiturates drugs that depress activity in the central nervous system and can lead to a variety of different effects. In some cases, they lead to anxiolytic and sedative effects, while in other cases they have more extreme anesthetic effects. It should be noted that the tolerance developed from this class of drugs is different than that of alcohol and benzodiazepines.

6. Crystal Meth

Its addiction rating is 2.24, according to the latest research. Crystal meth is a synthetic stimulant that when taken, generates feelings of artificial ecstasy. In comparison to the powder formulation of methamphetamine, crystal meth is considered to be of increased strength. Although, it is completely odorless, it significantly increases activity in the central nervous system.

7. Street Methadone

Its addiction rating is 2.08, while in latest research its 2.68, It is a drug that is commonly used for opioid replacement therapy and sometimes minor pain management. It is generally prescribed to an individual that is attempting to get off of a more extreme opioid like heroin or high dosages of pain pills. This drug also affects natural ability of the body to produce endorphins and is thought to influence various neurotransmitters such as dopamine.

8. Nicotine

Its addiction rate is 2.21, while in latest research its 2.82, Nicotine is a considered a very strong stimulant and is derived from the Solanaceae plant. At high doses of nicotine can be poisonous, while at lower doses (those used in tobacco) it produces stimulating effects. You may not think that nicotine is as damaging as cocaine, the fact is that nearly 20% of deaths each year in the United States are a result of tobacco products, all those contain nicotine. If we calculate, that means over 1,000 people are dying in the United States each day from deaths resulting from nicotine.

9. Cocaine

Its addiction rate is 2.39, while latest research tells its 2.82, Cocaine gives the user an intense high that is characterized by euphoria and stimulant effects on the central nervous system. Those who smoke crack are likely to feel increased social confidence, energetic, more alert and in some cases, as if they are on top of the world. These effects are achieved by the drug stimulating the release of dopamine in the brain.

10. Heroin

Its addiction rating is 3.0, It is considered an opioid analgesic drug that was developed in the 1870s by combining acetyl groups with the molecule morphine. This chemical ‘heroin’ itself does not have any effect, but when ingested by the body, it converts into morphine, and gives users a significant psychological and physical high. It acts as a depressant on the central nervous system, slowing down functioning throughout the body.

Aaric Hale

Aaric Hale is a writer whose expertise includes an array of topics across several industries—having done several articles on science, history, and the latest trends. Interested in the act of learning itself, he tries to keep his mind busy with exploring histories, global news, and about the world. Aaric Hale also wants to contribute to the popularization of science and communicate ideas across the globe.